The best replacement for py2exe is pyinstaller.

The best alternatives to py2exe are rated as following:
★★★★★  pyinstaller
★★  cx_freeze

Your alternative for py2exe is not listed? Suggest!
Speaking about py2exe, one probably shouldn't forget about pygame.

Other search terms related to py2exe and their ratings are:
★★★★★ pygame
★★★★ wxpython
★★★ tkinter
★★★ pyqt
You have in mind a companion for py2exe and it is not yet here? Propose!



Google Trends

Scale is based on the average worldwide traffic of py2exe in all years. Click on graph for more.
py2exe
pyinstaller
cx_freeze