The best replacement for pygame is pyglet.

The best alternatives to pygame are rated as following:
★★★★★  pyglet
★★★★★  pysdl2
★★★  love2d
★★★  kivy
★★  sdl
★★  sfml
★  libgdx
★  xna
  tkinter

Your alternative for pygame is not listed? Suggest!
Speaking about pygame, one probably shouldn't forget about tkinter.

Other search terms related to pygame and their ratings are:
★★★★★ tkinter
★★★★ python 3.3
★★ wxpython
★★ pyopengl
★ py2exe
★ gui
You have in mind a companion for pygame and it is not yet here? Propose!



Google Trends

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pygame
pyglet
pysdl2