The best replacement for gts 250 is gtx 260.

The best alternatives to gts 250 are rated as following:
★★★★★  gtx 260
★★★  gts 450
★★★  gt 630
★★  4850
★★  gtx 460
★★  hd 4850
★★  gt 640
★★  9800gtx
★★  8800gt
★  gtx 650 ti
★  9800 gt
★  gt 610
★  gtx 550 ti
★  9800
★  4870
★  9800 gtx
★  9800gt
  4770
  450
  hd4870
  hd 4770
  hd 6670
  8800 gtx
  ati 5770
  260
  gt 430
  8800 gts
  gts 260
  1gb ati radeon hd 4850
  radeon 4850
  5750

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gts 250
gtx 260
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