The best replacement for 4850 is 4870.

The best alternatives to 4850 are rated as following:
★★★★★  4870
★★★★★  5770
★★★★  9800gt
★★★  6670
★★★  8800gt
★★★  7770
★★  7750
★★  6850
★★  5450
★★  gtx 260
★★  5670
★★  9800gtx
★★  gts 250
★  6450
★  3870
★  9800
★  5750
★  6570
★  r7 250
★  hd 6770
★  4770
  9800 gtx
  8800 gtx
  6770
  gts250
  8800
  hd 4770
  4890
  hd 4870
  8800gts
  geforce 9800
  4830
  260
  nvidia 9800 gt
  hd 5670
  gtx

Your alternative for 4850 is not listed? Suggest!
Speaking about 4850, one probably shouldn't forget about 4870.

Other search terms related to 4850 and their ratings are:
★★★★★ 4870
★★ 4890
★ 4870 crossfire
★ 6850
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Google Trends

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4850
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