The best replacement for unresponsive is coma.

The best alternatives to unresponsive are rated as following:
★★★★★  coma
★★★★  nonresponsive
★★★★  unconscious
★★★★  non responsive
★★★  unresponsive
★★  responsive yoyo
  blocked
  comatose

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Google Trends

Scale is based on the average worldwide traffic of unresponsive in all years. Click on graph for more.
unresponsive
coma
nonresponsive