The best replacement for uncle is nephew.

The best alternatives to uncle are rated as following:
★★★★★  nephew
★★★★★  cousin
★★★★  great uncle
★★★★  uncle
★★★★  aunt
★★★  grand uncle
★  oncle
★  thrush
★  mom
★  aunty
  an uncle
  paran
  my uncle

Your alternative for uncle is not listed? Suggest!
Speaking about uncle, one probably shouldn't forget about niece.

Other search terms related to uncle and their ratings are:
★★★★★ niece
★★★★ peter dinklage
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uncle
nephew
cousin