The best replacement for tired is toxic.

The best alternatives to tired are rated as following:
★★★★★  toxic
★★★★★  lazy
★★★★  depressed
★★★  sleepy
★★★  exhausted
★★★  fatigue
★★  hungry
★★  tired
★★  driving drunk
★  wired
★  postpartum depression
★  sick
★  fatigued
★  decadent
★  did she just get lazy
★  tiring
★  bored
★  just lazy
★  dry eyes
★  tiered
★  being sick and tired
  tried
  drunk
  tipsy
  physically tired
  tierd
  worn out
  hungry baby
  to tired
  tireder
  drowsy
  driving while drunk
  weary

Your alternative for tired is not listed? Suggest!
Speaking about tired, one probably shouldn't forget about 8 hours of sleep.

Other search terms related to tired and their ratings are:
★★★★★ 8 hours of sleep
★★★ 7 hours of sleep
★ headaches all the time
You have in mind a companion for tired and it is not yet here? Propose!



Google Trends

Scale is based on the average worldwide traffic of tired in all years. Click on graph for more.
tired
toxic
lazy