The best replacement for soothe is calm.

The best alternatives to soothe are rated as following:
★★★★★  calm
★★★★  sooth
★★★★  gentle
★★★★  enfamil gentlease
★★★  systane
★★★  gentlease
★★★  similac sensitive
★★  ease
★★  nutramigen
★★  similac alimentum
★★  gerber soy
★★  gerber gentle
★  similac total comfort
★  enfamil ar
★  similac advance
★  enfamil newborn
★  not to soothe
  colic calm
  enfamil nutramigen
  quiet to calm

Your alternative for soothe is not listed? Suggest!

No companions for soothe have been suggested so far.
You have in mind a companion for soothe and it is not yet here? Propose!

Google Trends

Scale is based on the average worldwide traffic of soothe in all years. Click on graph for more.