The best replacement for soothe is calm.

The best alternatives to soothe are rated as following:
★★★★★  calm
★★★★  sooth
★★★★  gentle
★★★★  enfamil gentlease
★★★  systane
★★★  gentlease
★★★  similac sensitive
★★  ease
★★  nutramigen
★★  similac alimentum
★★  gerber soy
★★  gerber gentle
★  similac total comfort
★  enfamil ar
★  similac advance
★  enfamil newborn
★  not to soothe
  colic calm
  soothe
  enfamil nutramigen
  quiet to calm

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Google Trends

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