The best replacement for systane is refresh.

The best alternatives to systane are rated as following:
★★★★★  refresh
★★★  systane ultra
★★★  blink
★★  optive
★★  genteal
★★  thera tears
★★  visine
★★  refresh tears
★★  restasis
★  refresh optive
★  refresh eye drops
★  refresh plus
★  artificial tears
★  clear eyes
  tears naturale
  hypromellose
  soothe
  refresh which is better
  theratears
  rohto
  freshkote
  genteal eye drops
  celluvisc
  blink tears

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Google Trends

Scale is based on the average worldwide traffic of systane in all years. Click on graph for more.
systane
refresh
systane ultra