The best replacement for sirs is sepsis.

The best alternatives to sirs are rated as following:
★★★★★  sepsis
★★  madams
★★  gentlemen
★★  sir's
★  messrs
★  dear sir
★  septic shock
★  sir
★  mods
  ards
  dear sirs
  shock
  sir madam
  dear all

Your alternative for sirs is not listed? Suggest!
Speaking about sirs, one probably shouldn't forget about sepsis.

Other search terms related to sirs and their ratings are:
★★★★★ sepsis
You have in mind a companion for sirs and it is not yet here? Propose!



Google Trends

Scale is based on the average worldwide traffic of sirs in all years. Click on graph for more.
sirs
sepsis
madams