The best replacement for question is statement.

The best alternatives to question are rated as following:
★★★★★  statement
★★★★  hypothesis
★★★  query
★★  inquiry
★  any questions
★  answer
★  questions
★  rorschach
★  research hypothesis
★  request
★  riddler
★  research problem
★  concern
★  doubt
★  problem
  thesis statement
  exclamation mark
  justiciable question
  problem statement
  closed question
  comment
  hypotheses
  survey question
  circular reasoning
  closed ended question
  thesis
  non scientific question
  circular argument
  series of question
  leading question
  objective question
  interrogative
  close ended questions
  interrogate
  foreshadowed problem

Your alternative for question is not listed? Suggest!
Speaking about question, one probably shouldn't forget about answer.

Other search terms related to question and their ratings are:
★★★★★ answer
★★★ question mark
★★★ notice
★★ question
★★ question word
★ an answer
★ colon
★ must
★ obvious answer
expecting an answer
asking a question
should
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Google Trends

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question
statement
hypothesis