The best replacement for pc5300 is pc6400.

The best alternatives to pc5300 are rated as following:
★★★★★  pc6400
★★★★  pc5400
★★★  pc4200
★★★  pc3200
★★  pc2 5300
★★  pc2700
★★  pc2-5300
★  pc6400 ram
  pc2
  ddr2 pc5400
  pc25300

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Speaking about pc5300, one probably shouldn't forget about pc3200.

Other search terms related to pc5300 and their ratings are:
★★★★★ pc3200
★★★ pc6400
★ pc4200
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