The best replacement for pc2-5300 is pc2-6400.

The best alternatives to pc2-5300 are rated as following:
★★★★★  pc2-6400
★★★  pc2-4200
★★  pc2-5300f
★★  pc2-5300u
★  pc2-5300s
★  pc2-8500
★  pc2-3200
★  pc5300
★  6400
★  pc3200
★  pc2-5300p
★  pc-5300
★  ddr2 pc2-6400
  pc2100
  pc2-6400 ddr2
  ddr2 pc2-4200
  pc5400
  pc3-8500

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pc2-5300
pc2-6400
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