The best replacement for e550 is 550i.

The best alternatives to e550 are rated as following:
★★★★★  550i
★★★  e350
★★★  s550
★★  s6
★★  e63
★★  cls550
★★  bmw 550i
★  c63
★  e55
★  e500
★  ls460
★  2011 550i
★  m56
★  e6500
★  e55 amg
★  650i
★  f10
  ut50
  e63 amg
  bmw 550
  st50
  535i

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Google Trends

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e550
550i
e350