The best replacement for drug addiction is drug abuse.

The best alternatives to drug addiction are rated as following:
★★★★★  drug abuse
★★★  drug dependence
★★★  dependence
★★  alcoholism
★★  mental illness
★  abuse
★  drug dependent
★  physical dependence
  use
  food addiction
  dependency
  alcohol addiction
  recreational drug use
  gambling addiction
  drug use
  drug dependency
  shopping addiction

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Google Trends

Scale is based on the average worldwide traffic of drug addiction in all years. Click on graph for more.
drug addiction
drug abuse
drug dependence