The best replacement for deoxys is rayquaza.

The best alternatives to deoxys are rated as following:
★★★★★  rayquaza
★★★★★  mewtwo
★★★★★  mew
★★★★  arceus
★★★★  darkrai
★★★  lugia
★★  jirachi
★★  genesect
★  mewtwo who would win
★  rayquaza movie
★  giratina
★  rayquaza video
★  celebi
  rayquaza who would win
  groudon
  latios
  lucario

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deoxys
rayquaza
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