The best replacement for ccleaner is advanced systemcare.

The best alternatives to ccleaner are rated as following:
★★★★★  advanced systemcare
★★★★  malwarebytes
★★★★  registry mechanic
★★★  eraser
★★★  revo uninstaller
★★★  regcure
★★★  ccleaner pro
★★★  bleachbit
★★  onyx
★★  glary
★★  tuneup utilities
★★  window washer
★★  spybot
★★  jetclean
★★  cleanup
★★  iobit
★★  windows disk cleanup
★  glary utilities
★  fcleaner
★  wise
★  advanced systemcare free
★  registry booster
★  slimcleaner
★  disk cleanup
★  ccleaner slim
★  tuneup
★  ccleaner
★  comodo
★  privazer
  system mechanic
  dban
  dcleaner
  easy cleaner
  disc cleanup
  ncleaner
  cleanmymac
  wise registry cleaner
  eusing
  adaware
  revo
  disk doctor
  glary which is better
  regseeker
  easycleaner
  advanced system care

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Google Trends

Scale is based on the average worldwide traffic of ccleaner in all years. Click on graph for more.
ccleaner
advanced systemcare
malwarebytes