The best replacement for 2x12 is 4x10.

The best alternatives to 2x12 are rated as following:
★★★★★  4x10
★★★★★  4x12 cab
★★★★★  1x12
★★★★  4x12
★★★★  1x15
★★★★  2x10
★★★  4x10 bass cab
★★  i joist
★★  lvl
★  1x12 cab
★  tji
★  two 1x12
★  2x10 cab
★  1x12 combo
★  4x10 cab
★  4x10 cabinet
  4x10 bass
  1x12 amp
  bogner 2x12
  4x12 cabinet
  orange 2x12
  tgi
  4x8

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2x12
4x10
4x12 cab