The best replacement for 2i2 is saffire 6.

The best alternatives to 2i2 are rated as following:
★★★★★  saffire 6
★★★★★  ur22
★★★★  audiobox
★★★★  2i4
★★★  22vsl
★★  fast track pro
★★  mbox mini
★★  komplete audio 6
★★  duet 2
★  8i6
★  mobilepre
★  mackie blackjack
★  presonus 22vsl
★  mbox
  presonus audio box
  ux2

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2i2
saffire 6
ur22