The best replacement for 25-06 is 270.

The best alternatives to 25-06 are rated as following:
★★★★★  270
★★★★  243
★★★★  30-06
★★★  308
★★★  7mm-08
★★  22-250
★  6.5 creedmoor
★  260
★  270 wsm
★  270 recoil
★  6.5-06
★  7mm-08 recoil
★  257 roberts
★  257 weatherby
  280
  260 rem
  25 wssm
  257 weatherby magnum
  257
  7mm
  257 weatherby mag
  .257
  270 win
  6.5x55
  7mm mag
  243 ballistics
  .243

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25-06
270
243