The best replacement for 20s is 30s.

The best alternatives to 20s are rated as following:
★★★★★  30s
★★★  20's
★★  40s
★★  18s
★  30s buzzfeed
★  50s
★  twenties
  late 20s
  20g

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Speaking about 20s, one probably shouldn't forget about 33s.

Other search terms related to 20s and their ratings are:
★★★★★ 33s
★★★★ 35s
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Google Trends

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20s
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