The best replacement for .454 casull is .44 magnum.

The best alternatives to .454 casull are rated as following:
★★★★★  .44 magnum
★★★★  .44 mag
★★★  .45 colt
★★  .44
★★  .480 ruger
★  .45-70
★  .480
★  .460
  .500 s&w

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.454 casull
.44 magnum
.44 mag