The best replacement for .45 colt is .45 acp.

The best alternatives to .45 colt are rated as following:
★★★★★  .45 acp
★★★  .44 magnum
★★  .45 long colt
★★  .357
★★  .44 mag
★  .357 magnum
★  .357 mag
★  .44 special
★  .45 auto
★  long colt
  357 magnum
  acp
  45 lc
  .45 gap
  .44 40
  .454 casull
  .44

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.45 colt
.45 acp
.44 magnum