The best replacement for vs4621 is vs4121.

The best alternatives to vs4621 are rated as following:
★★★★★  vs4121
★★★★  vs2721
★★★★  z523
★★★  atp3
★★★  vs4121 altec lansing
★★  vs2621
★  fx3021

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vs4621
vs4121
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