The best replacement for vs2621 is z313.

The best alternatives to vs2621 are rated as following:
★★★★★  z313
★★★★  ca 3602
★★★★  z323
★★★  vs4621
★★★  creative t3130
★★  creative inspire t3130
★★  logitech z323
★★  octane 7
★  creative sbs a335
★  bxr1221
★  vs2721
★  cyber acoustics ca-3602
  sony srs d5
  logitech z313

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vs2621
z313
ca 3602