The best replacement for reason 6 is reason 5.

The best alternatives to reason 6 are rated as following:
★★★★★  reason 5
★★★★  ableton
★★★  komplete 8
★★★  logic 9
★★  ableton 8
★★  essentials
★  sonar x1
★  reason 7
★  logic pro 9
  reason essentials

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reason 6
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