The best replacement for q45 is ls430.

The best alternatives to q45 are rated as following:
★★★★★  ls430
★★★★★  ls400
★★★★★  m45
★★★  z32 brakes
★★  g45
★★  g41
★★  q35
★  lexus ls430
★  p45
★  q45t
★  gs400
  z32
  lexus 430

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q45
ls430
ls400