The best replacement for ls400 is q45.

The best alternatives to ls400 are rated as following:
★★★★★  q45
★★★★★  ls430
★★★  gs400
★★  sc400
★★  es300
★★  gs300
★  infiniti q45
★  ls 500
★  w140
★  740i
★  300sd
★  lph400
  acura legend
  e38
  lexus ls430
  celsior

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ls400
q45
ls430