The best replacement for light microscope is electron microscope.


The best alternatives to light microscope are rated as following:
★★★★★  electron microscope
★★★  compound microscope
★★★  dissecting microscope
★★  transmission electron microscope
★★  electron
★  stereo microscope
  optical microscope
  stereoscope
  confocal microscope
  scanning electron microscope
  electronic microscope
  dissecting
  electron microscopes
  tem

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Speaking about light microscope, one probably shouldn't forget about highest magnification.

Other search terms related to light microscope and their ratings are:

★★★★★ highest magnification
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light microscope
electron microscope
compound microscope