The best replacement for is300 is g35.

The best alternatives to is300 are rated as following:
★★★★★  g35
★★★  tsx
★★  is250
★★  gs300
★★  sc300
★  supra
★  is350
★  330i
★  rsx type s
  altezza
  gs400
  g35 sedan
  infiniti g35
  is200

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is300
g35
tsx