The best replacement for is250 is tsx.

The best alternatives to is250 are rated as following:
★★★★★  tsx
★★★★  is350
★★★  g35
★★  a4
★★  328i
★★  is300
★★  acura tsx
★  bmw 325i
★  bmw 328i
★  320i
★  es350
★  is250c
★  audi a4
★  tl
★  infiniti g35
★  c300
★  bmw 3 series
★  cla 250
★  g25
  325i
  acura tl
  ct200h
  bmw 325
  q50
  gs300
  mercedes c300
  infiniti g25
  lexus is350
  infiniti g37
  bmw 320
  325
  bmw 3
  is250 f sport

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Google Trends

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is250
tsx
is350