The best replacement for gilenya is tysabri.

The best alternatives to gilenya are rated as following:
★★★★★  tysabri
★★★★  tecfidera
★★★★  copaxone
★★★  avonex
★★★  rebif
★★  aubagio
★★  betaseron
★  bg 12
  bg12
  betaferon
  copaxon
  extavia

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Google Trends

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gilenya
tysabri
tecfidera