The best replacement for antagonist is protagonist.

The best alternatives to antagonist are rated as following:
★★★★★  protagonist
★★★★★  agonist
★★★  agonist muscles
★★  inverse agonist
★★  inhibitor
★★  villain
★  blockade
★  agonist ivf
★  synergist
★  agonist drugs
★  blocker
★  ppi
  agonist neurotransmitters
  opponent
  proton pump inhibitor
  villian
  long protocol
  microflare
  proton pump inhibitors
  agonist\/
  an agonist
  metro
  anticholinergic
  lupron protocol
  agonist psychology
  down regulation
  synergist muscles
  lupron
  adversary
  ace inhibitor

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