The best replacement for yamaha r6 is r1.

The best alternatives to yamaha r6 are rated as following:
★★★★★  r1
★★★  suzuki gsxr 600
★★★  r6s
★★★  honda cbr 600
★★  kawasaki zx6r
★★  gsxr 600
★★  cbr 600
★★  cbr600rr
★★  honda cbr600rr
★  honda cbr
★  ninja 650
★  honda 600rr
  yamaha r1
  gsxr 750
  ducati 899
  cbr
  daytona 675
  honda cbr 600rr
  cbr 600rr
  kawasaki ninja
  ktm duke 690
  ninja 650r
  gsxr
  suzuki gsxr 750
  ninja 636
  hyosung gt650r
  kawasaki zx 6r
  kawasaki 636
  honda f4i
  ducati 848

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yamaha r6
r1
suzuki gsxr 600