The best replacement for wyeast is white labs.

The best alternatives to wyeast are rated as following:
★★★★★  white labs
★  safale
★  dry yeast
★  white labs yeast
  white labs kolsch
  wlp
  danstar
  whitelabs

Your alternative for wyeast is not listed? Suggest!
Speaking about wyeast, one probably shouldn't forget about starter.

Other search terms related to wyeast and their ratings are:
★★★★★ starter
You have in mind a companion for wyeast and it is not yet here? Propose!



Google Trends

Scale is based on the average worldwide traffic of wyeast in all years. Click on graph for more.
wyeast
white labs
safale