The best replacement for tweetbot is twitter.

The best alternatives to tweetbot are rated as following:
★★★★★  twitter
★★★★★  echofon
★★★★  tweetdeck
★★★★  twitterrific
★★★  twitter iphone
★★  tweetlogix
★★  twitterrific 5
★★  tweetcaster
★★  hootsuite
★★  ubersocial
★★  twittelator neue
★★  twitter app
★  osfoora
★  tweetings
★  tweetlist
★  netbot
★  twitter for iphone
  slices

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Google Trends

Scale is based on the average worldwide traffic of tweetbot in all years. Click on graph for more.
tweetbot
twitter
echofon