The best replacement for touchwiz is sense.

The best alternatives to touchwiz are rated as following:
★★★★★  sense
★★★  nova
★★★  aosp
★★★  cyanogenmod
★★  sense 6
★★  google edition
★★  touchwiz easy
★  htc sense
★  go launcher
★  lg ui
★  sense ui
★  ios 7
★  motoblur
★  go launcher ex
★  launcher pro
★  stock s4
★  sense 5
★  apex launcher
★  stock android
★  trebuchet
★  htc sense 5
  optimus ui
  adw
  easy launcher
  timescape
  vanilla
  sony ui
  launcher
  kitkat

Your alternative for touchwiz is not listed? Suggest!
Speaking about touchwiz, one probably shouldn't forget about kitkat.

Other search terms related to touchwiz and their ratings are:
★★★★★ kitkat
★ ics
You have in mind a companion for touchwiz and it is not yet here? Propose!



Google Trends

Scale is based on the average worldwide traffic of touchwiz in all years. Click on graph for more.
touchwiz
sense
nova