The best replacement for tosa is pitbull.

The best alternatives to tosa are rated as following:
★★★★★  pitbull
★★★  kangal
★★  boerboel
★★  akita
★★  pit
★★  bully kutta
★  presa canario
★  presa
★  apbt
★  caucasian ovcharka
  cao
  fila
  tisa
  dogo
  pit bull

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Google Trends

Scale is based on the average worldwide traffic of tosa in all years. Click on graph for more.
tosa
pitbull
kangal