The best replacement for tophi is rheumatoid nodules.

The best alternatives to tophi are rated as following:
★★★★★  rheumatoid nodules

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Speaking about tophi, one probably shouldn't forget about gout.

Other search terms related to tophi and their ratings are:
★★★★★ gout
★★ chronic gout
intravenous peg uricase in refractory gout
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