The best replacement for thanos is darkseid.

The best alternatives to thanos are rated as following:
★★★★★  darkseid
★★★★  galactus
★★★★  hulk
★★★  superman
★★  apocalypse
★★  odin
★★  thor
★★  doomsday
★  silver surfer
★  ultron
★  avengers
★  juggernaut
  onslaught
  tyrant
  black bolt
  phoenix
  zeus
  sentry
  red skull
  living tribunal
  magneto
  dr doom
  doom
  captain marvel
  superman prime

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Google Trends

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thanos
darkseid
galactus