The best replacement for thalidomide is lenalidomide.

The best alternatives to thalidomide are rated as following:
★★★★★  lenalidomide
★★★  revlimid
★  velcade

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Speaking about thalidomide, one probably shouldn't forget about dexamethasone.

Other search terms related to thalidomide and their ratings are:
★★★★★ dexamethasone
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