The best replacement for sulfasalazine is methotrexate.

The best alternatives to sulfasalazine are rated as following:
★★★★★  methotrexate
★★★★  asacol
★★★  lialda
★★★  balsalazide
★★★  mesalamine
★★  pentasa
★★  sulfadiazine
★★  sulfazine
★  colazal
★  apriso
★  salofalk
★  sulfasalazine ec
★  5 asa
  plaquenil
  azulfidine
  mesalazine

Your alternative for sulfasalazine is not listed? Suggest!
Speaking about sulfasalazine, one probably shouldn't forget about folic acid.

Other search terms related to sulfasalazine and their ratings are:
★★★★★ folic acid
You have in mind a companion for sulfasalazine and it is not yet here? Propose!



Google Trends

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sulfasalazine
methotrexate
asacol