The best replacement for suffixes is prefixes.

The best alternatives to suffixes are rated as following:
★★★★★  prefixes
★★★★★  er
★★★★★  and er
★★★★★  suffices
★  meanings
  word list
  suffixes

Your alternative for suffixes is not listed? Suggest!
Speaking about suffixes, one probably shouldn't forget about able.

Other search terms related to suffixes and their ratings are:
★★★★★ able
You have in mind a companion for suffixes and it is not yet here? Propose!



Google Trends

Scale is based on the average worldwide traffic of suffixes in all years. Click on graph for more.
suffixes
prefixes
er