The best replacement for stimulants is depressants.

The best alternatives to stimulants are rated as following:
★★★★★  depressants
★★★★★  non stimulants
★★★  uppers
★★★  opiates
★★★  on adrenergic agonists
★★  strattera
★★  depressants more dangerous
★★  antidepressants
★  psychedelics
★  amphetamines
★  amphetamine stimulants
★  narcotics
★  sedatives
  nonstimulants
  depressants drugs
  cns depressants
  methylphenidate stimulants

Your alternative for stimulants is not listed? Suggest!
Speaking about stimulants, one probably shouldn't forget about antidepressants.

Other search terms related to stimulants and their ratings are:
★★★★★ antidepressants
★★★ benzodiazepines
★★★ adhd
★★★ antipsychotics
★★ depressants
★ benzos
You have in mind a companion for stimulants and it is not yet here? Propose!



Google Trends

Scale is based on the average worldwide traffic of stimulants in all years. Click on graph for more.
stimulants
depressants
non stimulants