The best replacement for sprained ankle is broken ankle.

The best alternatives to sprained ankle are rated as following:
★★★★★  broken ankle
★★★  fracture
★★★  broken
★★  break
★  torn ligament
★  torn ligaments
★  twisted ankle
★  broken foot
★  hairline fracture
★  blood clot
★  rolled ankle
  strained ankle
  fractured ankle
  torn tendon
  sprained ankle
  broken bone
  broken ankle symptoms
  strained

Your alternative for sprained ankle is not listed? Suggest!
Speaking about sprained ankle, one probably shouldn't forget about bruising.

Other search terms related to sprained ankle and their ratings are:
★★★★★ bruising
★★★★ swelling
★★★ no swelling
★★ numb toes
★ numbness
★ swollen foot
★ swelling toes
★ burning pain
★ bruised toes
tingling toes
popping sound
bone chip
crutches
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Google Trends

Scale is based on the average worldwide traffic of sprained ankle in all years. Click on graph for more.
sprained ankle
broken ankle
fracture