The best replacement for simpsons is family guy.

The best alternatives to simpsons are rated as following:
★★★★★  family guy
★★★★  south park
★★★  futurama
★★  rick and morty
★  griffins
★  fox news
★  family guy ratings
★  king of the hill
★  cosby show
★  family guy poll
★  american dad
  jetsons
  seinfeld
  spongebob
  family guy better
  homer
  flintstones
  futurama family guy
  southpark

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Speaking about simpsons, one probably shouldn't forget about family guy.

Other search terms related to simpsons and their ratings are:
★★★★★ family guy
★ simpsons
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Google Trends

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simpsons
family guy
south park