The best replacement for simplex is duplex.

The best alternatives to simplex are rated as following:
★★★★★  duplex
★★  duplex fiber
★★  herpes zoster
★★  half duplex
★★  duplex scanning
★  zoster
★  shingles
★  perlin
  interior point
  genital herpes
  duplex fibre
  lichen sclerosis
  multiplex
  semi duplex
  cold sores
  duplex fiber optic cable
  duplex scanners
  duplex mode
  full duplex
  herpes complex
  halfduplex

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Google Trends

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simplex
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