The best replacement for seafile is owncloud.

The best alternatives to seafile are rated as following:
★★★★★  owncloud
★★★★  bittorrent sync
★★★  sparkleshare
★★★  pydio

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Google Trends

Scale is based on the average worldwide traffic of seafile in all years. Click on graph for more.
seafile
owncloud
bittorrent sync