The best replacement for saffire is firebox.

The best alternatives to saffire are rated as following:
★★★★★  firebox
★★★★★  scarlett
★★★★  mbox
★★  firestudio
★  motu
★  firepod
★  motu ultralite
★  presonus firestudio
  mbox2

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Google Trends

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saffire
firebox
scarlett