The best replacement for refissa is renova.

The best alternatives to refissa are rated as following:
★★★★★  renova
★★★★  tretinoin
★★★★  retin a
★★  tazorac
★  retin a micro
★  atralin
  retina a
  stieva-a

Your alternative for refissa is not listed? Suggest!
Speaking about refissa, one probably shouldn't forget about obagi blender.

Other search terms related to refissa and their ratings are:
★★★★★ obagi blender
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refissa
renova
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